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Product code: DKIOP50

DKI OLEUROPEIN PHENO 50g

Brand: EASY REEFS

19,90 €
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DKI OLEUROPEIN PHENO

50g




THE NEW ADVANCED EASYREEFS PROGRAM


Oleuropein (OLE) is a phenolic compound found in all parts of the olive tree, mainly in the leaves. In the search for natural, safe, selective and environmentally friendly treatments to combat fish diseases, several studies have demonstrated the suitability and efficacy of OLE against several pathogens.


For example, salmonid haemorrhagic septicemia virus (VHSV), a salmonid rhabdovirus that infects farmed fish in inland and marine waters, as well as a wide range of wild marine species worldwide, causing huge economic losses every year. OLE has been shown to inhibit the infectivity of VHSV in vitro, so it is considered a lead compound for the design of potential therapeutic agents for other rhabdoviruses and/or enveloped viruses.


Furthermore, olive leaf extracts, as a source of OLE, were shown to be effective when supplied in the diet against bacterial infections such as: i) Yersininia ruckeri, inducing the positive regulation of key genes involved in the stimulation of the immune response, such as TNF-α, IL-8 and IL-1β, and ii) Edwardsiella tarda, increasing the survival rate and improving the immune parameters of fish, revealed by the significant upregulation of IL-1β and TNF-α. Finally, the direct anti-inflammatory properties of OLE include the downregulation of: i) iNOS and COX-2, two key inflammatory markers, and ii) IL-1β and IL-6, two critical proinflammatory cytokines.

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